I've moved my 50 gallon with the sand in it several times with no issues. The move itself shouldn't cause the tank to crack (dropping or hitting it against something could). If its a short move, you should take as much water out as possible (less to lift). As long as the sand stays moist the bacteria shouldn't be negatively impacted.

HTH,
Tom

Warning
Remember to lift with your knees and don't lift it by the top rim-stock.