Well you should only get into an inaccuracy if you were to get down the point where the air gap is being dispensed. Second you can get more consistent by drawing a full syringe and then push it right back into the bottle hard, some of the air will then leave the syringe. But really it's a non issue unless your pushing air out of the syringe while still doing the titration. You will still have moved as much titration fluid into your sample as compared to the syringe being completely full of fluid. Does that crap make sense, lol. Bottom line if you don't see air bubbles in the syringe tip then your just fine.